Altren

Synthetic progestogen (altrenogest) to suppress estrus in mares, maintain pregnancy, synchronize estrus for breeding/embryo transfer, and suppress estrus-related behavior. Synthetic progestogen (altrenogest). Mechanism: progesterone receptor agonist that suppresses LH/FSH release via negative feedback on the hypothalamic-pituitary axis, inhibiting ovulation and maintaining uterine quiescence. 0.22% solution in oil (Regu-Mate). High transdermal absorption — CAUTION: human exposure hazardous. Key information HUMAN SAFETY CRITICAL: Wear chemical-resistant gloves; avoid skin contact — absorbed dermally and causes uterine/menstrual disruption in women. Pregnant women and women of childbearing age must not handle. Store at room temperature. Progestogen used for estrus suppression in mares.

Oral: administer via dose syringe directly into the mare's mouth or mix into a small portion of grain. Wear chemical-resistant gloves at all times — dangerous human skin absorption. Store at room temperature; protect from light. Shake well before use. Administer at the same time each day. If a dose is missed This product is given as a single dose or as part of a defined protocol. Contact your veterinarian if a scheduled administration was missed. Altren is part of a specific reproductive protocol — contact your veterinarian.

Behavioral changes (suppression of estrus, possible aggression changes). Uterine fluid accumulation possible if used in mares with active infections. Human safety: strong dermal absorption — causes menstrual cycle disruption, fertility effects, potential teratogenicity in exposed women.

For animals Use caution in mares with active uterine infection — may trap pathogens under progesterone-mediated suppression. Do not use in mares intended for human consumption. Use with caution in pregnant animals. (intended use is pregnancy maintenance but dose and timing critical). Remove from feed gradually rather than abrupt discontinuation to prevent estrus rebound. For people handling this medication DANGER: Altrenogest is readily absorbed through human skin and is a potent reproductive hazard. Pregnant women and women of childbearing age must NOT handle this product — it can cause serious hormonal disruption and fetal harm. Wear chemical-resistant gloves (nitrile or neoprene — NOT latex). Wear protective clothing covering all skin. If skin contact occurs, wash immediately with soap and water for at least 15 minutes. If eye contact occurs, flush with water for 15 minutes and seek immediate medical attention. Keep out of reach of children. Contact Poison Control (1-800-222-1222) or seek emergency care for any significant exposure.

Contact your veterinarian. Altrenogest overdose causes prolonged progestogenic effects. Human exposure requires immediate medical attention — call Poison Control (800-222-1222).