Amox/k Clav Sus 200/5ml

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General Drug Information and Indications

Susceptible bacterial infections (respiratory, urinary, skin, soft tissue, dental) in dogs, cats, and horses; amox/clav extends spectrum to beta-lactamase-producing organisms. Aminopenicillin antibiotic (amoxicillin ± clavulanate). Mechanism: inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing peptidoglycan cross-linking (bactericidal). Amoxicillin: acid-stable, orally bioavailable. Clavulanate: beta-lactamase inhibitor extending spectrum to resistant organisms (Staph, E. coli, Pasteurella). Key information Store suspension in refrigerator; discard after 14 days. Shake well before use. Do not use in rabbits, guinea pigs, hamsters, or other hindgut fermenters — fatal enterocolitis. Cross-reactive with penicillin allergy. Short post-antibiotic effect — strict dosing intervals important.

How to Give this Medication

Oral tablets/chewables: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. (especially amoxicillin-clavulanate — food reduces GI effects). Oral suspension: Shake well before each use. Store refrigerated (2–8°C); do not freeze. Injectable (amoxicillin trihydrate suspension): Administer IM only — never IV. — shake well, inject deep IM. Complete full course. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Complete the full antibiotic course.

Side Effects

GI: diarrhea, vomiting, anorexia (particularly in cats). Hypersensitivity reactions: urticaria, pruritus, angioedema, anaphylaxis. Superinfection with resistant organisms. Clavulanate component increases GI adverse effects vs. amoxicillin alone.

Precautions

For animals Penicillinase-sensitive — confirm susceptibility before use in infections likely involving beta-lactamase-producing organisms. With clavulanate: extended spectrum but increased GI adverse effects. Do not use in patients with known beta-lactam hypersensitivity. Small herbivores (rabbits, guinea pigs, hamsters): contraindicated — fatal Clostridium-associated enterocolitis. Time-dependent killing — dosing interval critical. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Penicillin-class antibiotic — inform your doctor if you have penicillin allergy. Wash hands after administering to pets.

Overdose

Contact your veterinarian. Amoxicillin/clavulanate overdose typically causes GI upset. Contact vet for guidance.

Amox/k Clav Sus 200/5ml dosage forms

ProductStrengthFormSizeType
AMOX/K CLAV SUS 200/5ML——5MLCommercial
AMOX/K CLAV SUS 200/5ML——5MLCommercial
AMOX/K CLAV SUS 200/5ML——5MLCommercial
AMOX/K CLAV TAB 500-125 - 20 TABS500 MG (SANDOZ)Tablet1Commercial
AMOX/K CLAV TAB 875-125—Tablet1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Penicillins Use in Animals (https://www.merckvetmanual.com/pharmacology/antibacterial-agents/use-of-penicillins-in-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)