Arthrex Irap Ii System

Autologous conditioned serum (IRAP) for intra-articular treatment of equine joint disease; concentrates anti-inflammatory cytokines from patient's blood for osteoarthritis. Autologous conditioned serum (ACS) preparation system. Blood incubated with chromium sulfate-coated glass beads stimulates monocytes/macrophages to produce anti-inflammatory cytokines (especially IL-1 receptor antagonist/IL-1Ra). Concentrated serum injected intra-articularly to competitively inhibit IL-1 binding and cartilage degradation.

Intra-articular injection: performed by veterinarian under strict aseptic conditions. Blood is collected from the patient, incubated with chromium sulfate-coated beads, centrifuged, and the resulting conditioned serum is injected intra-articularly. Use immediately after processing. Multiple joint injections possible from one blood collection.

Intra-articular injection: mild transient synovitis and joint effusion (normal inflammatory response). Injection site reactions. Risk of infection with any intra-articular injection (aseptic technique critical).

For animals Intra-articular ACS — aseptic technique essential. Restrict exercise 24–48 hrs post-injection. Do not use in joints with active septic arthritis. Blood collection from donor horse requires aseptic venipuncture. For people handling this medication Administered by veterinary professionals only. No specific human precautions for caregivers beyond normal hygiene.