Aservo Equihaler

General Drug Information and Indications

Inhaled ciclesonide (equine-specific inhaler) for management of equine asthma (recurrent airway obstruction); corticosteroid delivered directly to airways. Inhaled corticosteroid (ciclesonide) delivered via equine-specific metered-dose inhaler. Prodrug activated in the lung to des-ciclesonide. Potent topical glucocorticoid receptor agonist; inhibits phospholipase A2 via annexin-1 induction → reduced arachidonic acid release → decreased prostaglandin and leukotriene synthesis. High first-pass metabolism minimizes systemic effects. Key information For equine use only. Shake well before each use. Prime device before first use and after storage >5 days. Store at room temperature. Corticosteroid — systemic absorption possible. Do not expose to temperatures above 50°C.

How to Give this Medication

Inhaled (equine MDI): use the Aservo EquiHaler device only. Hold device to nostril during natural inhalation; administer prescribed number of puffs. Store at room temperature; protect from light. Shake before use. Prime per manufacturer instructions. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Side Effects

Inhaled corticosteroid: minimal systemic effects. Local: coughing at time of administration. Adrenal suppression rare at labeled equine doses. HFA propellant: inhalation irritation possible.

Precautions

For animals Inhaled corticosteroid — use appropriate equine inhaler device (Aservo EquiHaler). Not for acute bronchospasm. Monitor for adrenal suppression with prolonged use. Not for use in horses with active respiratory infections without concurrent antimicrobial therapy. For people handling this medication Wash hands thoroughly with soap and water after handling. Inhaled corticosteroid — avoid breathing aerosol. Wash hands after use. Keep out of reach of children.

Overdose

Contact your veterinarian. Excessive inhalation of corticosteroid may cause adrenal suppression. Signs include lethargy and reduced appetite.

Aservo Equihaler dosage forms

ProductStrengthFormSizeType
ASERVO EQUIHALER 343 MCG/ACTUATION INH343 MCG—1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)