Atenolol Tab

Beta-1-selective adrenergic antagonist for cardiac arrhythmias, hypertension, and hypertrophic cardiomyopathy in dogs and cats. Cardioselective beta-1 adrenergic receptor antagonist (beta-blocker). Mechanism: competitively blocks beta-1 receptors in the heart → reduced heart rate, contractility, and AV nodal conduction velocity. Beta-1 selectivity is dose-dependent. Orally bioavailable; renally excreted. Does not cross blood-brain barrier significantly. Key information Do not abruptly discontinue — taper dose over 2 weeks. Contraindicated in bradycardia, AV block, decompensated heart failure. Mask signs of hypoglycemia. Store at room temperature.

Oral tablets: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. or without food. Tablets may be crushed and mixed into food for compliance. Administer at consistent times daily. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember. If the next dose is due within a few hours, skip the missed dose and resume the regular schedule. Never give a double dose. Never abruptly stop atenolol — taper under veterinary guidance.

Bradycardia, hypotension, AV block. CNS: lethargy, depression, exercise intolerance. GI: vomiting, diarrhea. Bronchospasm (beta-2 blockade, even with selective agent at higher doses — use caution in respiratory disease). Masking of hypoglycemia signs in diabetics. Rebound hypertension/tachycardia with abrupt discontinuation.

For animals Avoid in patients with AV block (>1st degree), sinus bradycardia, cardiogenic shock, or decompensated heart failure. Use with caution in patients with diabetes (masks hypoglycemia signs), renal impairment, or respiratory disease (bronchospasm risk even with selective agents). Do not abruptly discontinue — taper slowly. Reduce dose or extend interval in renal impairment. Not approved for use in food-producing animals. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Beta-blocker — even small doses can cause bradycardia in children. Store securely. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact.

Contact your veterinarian or emergency clinic immediately. Beta-blocker overdose causes severe bradycardia, low blood pressure, and heart block. Emergency treatment includes atropine and glucagon.