Atropine Sul Sol

Anticholinergic for preanesthetic medication, bradycardia treatment, and bronchospasm; ophthalmic mydriasis, cycloplegia, and uveitis; organophosphate/carbamate toxicity antidote. Anticholinergic agent (muscarinic receptor antagonist). Mechanism: competitively blocks muscarinic acetylcholine receptors (M1–M5) → inhibits parasympathetic effects: increases HR (M2 block), reduces GI motility and secretions (M3 block), dilates bronchioles, produces mydriasis and cycloplegia (M3). Antidote for organophosphate/carbamate toxicity: reverses cholinergic crisis. Hepatically metabolized. Key information Store at room temperature; protect from light. Onset within 1–2 min IV. Causes ileus in horses — use for ophthalmic purposes only (systemic absorption via nasolacrimal duct). Antidote for organophosphate/carbamate toxicity. Reversal: physostigmine (CNS effects).

Injectable: IV (dilute, give slowly), IM, or SQ. Ophthalmic solution: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. 1% solution for cycloplegia/mydriasis; 2–3 drops q8–24h. Oral: Administer orally. May be given with food to improve compliance and reduce GI upset. For organophosphate antidote: repeat IV dosing every 5–10 min until secretions are controlled (salivation, lacrimation, bronchospasm). Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Tachycardia, dry mouth, decreased GI motility/ileus, urinary retention, mydriasis, cycloplegia. CNS: excitement, delirium, seizures (high doses). Reduced lacrimation. Horses: ileus, colic. GI: bloat in cattle. Avoid in tachycardia, glaucoma, GI obstruction.

For animals Contraindicated in patients with tachyarrhythmias, glaucoma (angle-closure), GI obstruction, or urinary obstruction. Use with caution in horses and cattle — can precipitate ileus and bloat. High doses cause CNS excitability. Antidote for organophosphate toxicity: repeat dosing until secretions are controlled. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Anticholinergic — avoid accidental ingestion (causes tachycardia, dry mouth, blurred vision). Ophthalmic solution: avoid eye contact. If ingested, contact Poison Control. Keep out of reach of children.

Contact your veterinarian. Atropine overdose causes anticholinergic toxidrome: fixed dilated pupils, rapid heart rate, dry mouth, hyperthermia, urinary retention, and delirium. Emergency supportive care required.