Baytril

Fluoroquinolone antibiotic (enrofloxacin) for susceptible gram-negative and gram-positive bacterial infections in horses, dogs, and cats. Fluoroquinolone antibiotic (enrofloxacin). Mechanism: inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV → prevents DNA replication and transcription (bactericidal). Concentration-dependent killing with post-antibiotic effect. Broad gram-negative and gram-positive spectrum. Penetrates well into tissues and cells. Key information Do NOT use in growing/young animals — causes cartilage damage. Avoid in horses under 2 years. Do not give IV rapidly — seizures reported. Store at room temperature. Fluoroquinolone — resistance monitoring important. Retinal toxicity in cats at high doses — use cautiously.

Oral tablets: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. Separate from antacids, dairy, and iron by 2 hrs. Injectable: IV (dilute in 0.9% NaCl; infuse over 30–60 min — do NOT give rapid IV bolus), SQ, or IM as labeled. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Complete the full antibiotic course.

GI: vomiting, diarrhea, anorexia. Cartilage toxicity in growing animals (avoid in dogs <12 months, cats <12 months, foals). CNS: seizures, tremors (rare — high doses or IV too rapid). Nephrotoxicity (rare). Cats: retinal toxicity and blindness (high doses — do not exceed 5 mg/kg/day).

For animals CONTRAINDICATED in growing animals with open growth plates — articular cartilage damage (dogs <12 months, cats, foals). Cats: do not exceed 5 mg/kg/day — risk of irreversible retinal degeneration and blindness. Do not administer rapid IV (seizure risk). Monitor renal function, hydration status, and urine output. Drug interactions: divalent cations (antacids, dairy, iron, sucralfate) reduce oral absorption — separate by 2 hrs. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Fluoroquinolone antibiotic — Wash hands thoroughly with soap and water after handling. after handling. Avoid sun exposure on skin contacted by drug (photosensitivity). Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact.

Contact your veterinarian immediately. Enrofloxacin overdose causes vomiting, neurological signs (seizures), and retinal damage in cats. Contact your veterinarian, a veterinary emergency clinic, or the ASPCA Animal Poison Control Center (888-426-4435) immediately. Do not induce vomiting unless specifically directed by a veterinary professional.