Bio-mycin 200 (oxytet)

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General Drug Information and Indications

Long-acting oxytetracycline for susceptible bacterial infections in cattle and horses including respiratory disease, pinkeye, and anaplasmosis. Long-acting oxytetracycline injectable. Mechanism: bacteriostatic tetracycline — reversibly binds 30S ribosomal subunit → blocks aminoacyl-tRNA binding to mRNA-ribosome complex → inhibits bacterial protein synthesis. Broad spectrum including gram-positive, gram-negative, rickettsiae, Mycoplasma. Long-acting formulation (LA-200) provides sustained tissue levels for 3–5 days. Key information Oxytetracycline long-acting injectable. Refrigerate. Deep IM injection only — IV/SC causes severe tissue necrosis. Beef withdrawal: 28 days. Milk: 96 hours. Shake well.

How to Give this Medication

Injectable: administer SQ in cattle, or as directed. Horses: IV (diluted) preferred; avoid IM (tissue necrosis). Shake well before each use. before use. Rotate injection sites with repeat dosing. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

Tissue necrosis at injection site (IM — especially 200 mg/mL formulation in wrong muscle). GI: diarrhea, anorexia. Phototoxicity (cattle). Renal/hepatic toxicity with high doses. Hypersensitivity reactions (rare). Superinfection. Horses: not approved; use with caution.

Precautions

For animals IM injection in horses: severe tissue necrosis risk with high-concentration formulation — use with care and limit injection volumes. Observe food animal withdrawal times for milk and meat. Avoid in patients with renal or hepatic impairment. Use with caution in pregnant animals. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Injectable oxytetracycline — avoid skin and eye contact. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. (tetracyclines affect bone/tooth development in fetuses). Wear gloves for handling and administration.

Overdose

Contact your veterinarian. Long-acting oxytetracycline overdose causes tissue injury and potential renal toxicity.

Bio-mycin 200 (oxytet) dosage forms

ProductStrengthFormSizeType
BIO-MYCIN 200 (OXYTET) - 100ML——1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)