Buserelin Acetate 10 Ml
General Drug Information and Indications
GnRH agonist for induction of ovulation in mares; synchronization of ovulation for breeding; treatment of ovarian cysts in cattle.
Synthetic GnRH agonist (gonadotropin-releasing hormone analogue). Mechanism: stimulates GnRH receptors on pituitary gonadotrophs → LH and FSH surge → ovulation induction within 36–48 hrs in mares. More potent and longer-acting than native GnRH. Used for synchronization of ovulation in breeding programs.
Key information
GnRH analogue — refrigerate. Administer exactly as directed for timing protocols. Do not shake vigorously. Wear gloves when handling — hormonal contamination risk.
How to Give this Medication
IM or SQ injection: administer as directed. Mares: confirm follicle ≥35 mm by ultrasound before administration. Expect ovulation within 36–48 hrs — confirm by ultrasound. Store refrigerated (2–8°C); do not freeze.
If a dose is missed
This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.
Side Effects
Transient reduction in libido and spermatogenesis in stallions with repeated use. Mares: multiple ovulations possible → twin pregnancy risk (monitor ultrasonographically). Injection site reactions (mild). Antibody formation with repeated use may reduce efficacy.
Precautions
For animals
Mares: monitor by ultrasound for ovulation and for multiple follicles (twin pregnancy risk). Stallions: repeated use may cause antibody formation — monitor breeding efficacy. Not for use in mares with cystic ovaries or prolonged diestrus without pre-treatment.
For people handling this medication
Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Synthetic GnRH — avoid skin contact. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Hormonal drug — women of childbearing age should take extra care.
Overdose
Contact your veterinarian. GnRH analogue overdose causes initial hormonal surge then suppression. Contact vet for guidance.
Buserelin Acetate 10 Ml dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| BUSERELIN ACETATE 10 ML 25 MCG/ML INJECTABLE | 25 MCG/ML | Injectable | 1 | Compound |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Systemic Pharmacotherapeutics of the Reproductive System (https://www.merckvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-reproductive-system/overview-of-systemic-pharmacotherapeutics-of-the-reproductive-system-in-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)