Cefepime Inj

Fourth-generation cephalosporin with extended gram-negative coverage including Pseudomonas; severe bacterial infections. Fourth-generation cephalosporin antibiotic. Mechanism: binds PBPs → inhibits cell wall synthesis (bactericidal). Extended spectrum vs. third-generation: stable against most AmpC beta-lactamases; effective against Pseudomonas aeruginosa and many gram-negative bacilli. Time-dependent killing. Key information Fourth-generation cephalosporin. Reconstitute per label; refrigerate reconstituted solution. IV infusion over 30 min. Reserved for resistant gram-negative infections. Monitor renal function.

IV: dilute in 0.9% NaCl or D5W; administer over 30 min. IM: reconstitute and inject deep IM. Store refrigerated (2–8°C); do not freeze. (reconstituted solution). If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

GI: diarrhea, vomiting, nausea. Hypersensitivity (cross-reactive with other beta-lactams). CNS: encephalopathy, seizures (high doses or renal impairment — dose adjust). Phlebitis (IV). Superinfection.

For animals Reduce dose or extend interval in renal impairment. — dose-reduce in renal impairment; risk of encephalopathy at normal doses in patients with CKD. Avoid in beta-lactam-hypersensitive patients. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Cephalosporin — inform your doctor if you have beta-lactam allergy. Wash hands thoroughly with soap and water after handling.

Contact your veterinarian. IV cephalosporin overdose may cause seizures (especially with renal impairment). Supportive care required.