Cefpoderm (k9)

General Drug Information and Indications

Third-generation oral cephalosporin (cefpodoxime) for skin, soft tissue, and urinary tract infections in dogs and cats. Third-generation oral cephalosporin (cefpodoxime proxetil — prodrug). Mechanism: binds PBPs → inhibits cell wall synthesis (bactericidal). Extended gram-negative coverage compared to first-generation. Proxetil ester hydrolyzed to active cefpodoxime after absorption. Good oral bioavailability in dogs (~90%). Key information Cefpodoxime proxetil — third-generation oral cephalosporin for dogs. Administer with food. Store at room temperature. Do not use in rabbits or hindgut fermenters.

How to Give this Medication

Oral tablets: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. to enhance absorption and reduce GI effects. Complete full course. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Complete the full antibiotic course.

Side Effects

GI: vomiting, diarrhea, anorexia (most common adverse effects). Hypersensitivity: skin rash, urticaria, anaphylaxis. Superinfection.

Precautions

For animals Avoid in beta-lactam-hypersensitive patients. Reduce dose or extend interval in renal impairment. Dogs: give with food to improve tolerability. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Cephalosporin — inform your doctor if you have beta-lactam allergy. Wash hands thoroughly with soap and water after handling.

Overdose

Contact your veterinarian. Cephalosporin overdose usually causes GI signs.

Cefpoderm (k9) dosage forms

ProductStrengthFormSizeType
CEFPODERM (K9) 200MG (Dechra)200 MG—1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)