Chorulon 10000 Usp Units/ Vial Injectable

General Drug Information and Indications

Human chorionic gonadotropin (hCG) for induction of ovulation in mares and treatment of ovarian cysts; LH-like activity. Human chorionic gonadotropin (hCG) — glycoprotein hormone. Mechanism: binds LH/CG receptors on ovarian follicle theca and granulosa cells → triggers LH receptor signaling cascade → ovulation within 36–48 hours. Structurally similar to LH with longer half-life. May develop antibodies with repeated use. Key information hCG — refrigerate. Reconstitute immediately before use; use within 6–8 hours. Administer IV or IM only. Antibody formation with repeated use may reduce efficacy. Store lyophilized powder at room temp.

How to Give this Medication

IV or IM injection: reconstitute powder with provided diluent; administer IV or IM. Horses: administer when follicle is ≥35 mm; confirm ovulation by ultrasound 36–48 hrs later. Use immediately after reconstitution. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

Mares: twinning (multiple ovulations — ultrasonographic monitoring required). Antibody formation with repeated use → reduced efficacy. Stallions: cryptorchidism stimulation test — mild scrotal edema. General: injection site reactions.

Precautions

For animals Mares: monitor by ultrasound for multiple ovulations (twin pregnancy risk — manual reduction may be required). Repeated use: antibody formation → reduced LH-like efficacy. Ensure follicle is ≥35 mm before administration for best ovulation results. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Gonadotropin hormone — Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Women of childbearing age should avoid skin contact. Wear gloves.

Overdose

Contact your veterinarian. hCG overdose may cause ovarian hyperstimulation. Supportive care as needed.

Chorulon 10000 Usp Units/ Vial Injectable dosage forms

ProductStrengthFormSizeType
CHORULON 10000 USP UNITS/ VIAL INJECTABLE—Injectable1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Systemic Pharmacotherapeutics of the Reproductive System (https://www.merckvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-reproductive-system/overview-of-systemic-pharmacotherapeutics-of-the-reproductive-system-in-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)