Citric Acid, Magnesium Oxide & Sodium Bicarbonate

Alkalinizing agent for metabolic acidosis; oral supplementation in horses with tying-up; buffering agent in compounded formulations. Alkalinizing buffer (sodium bicarbonate). Mechanism: HCO3- directly neutralizes hydrogen ions → corrects metabolic acidosis; increases blood and urine pH. Used IV for metabolic acidosis, hyperkalemia (shifts K+ into cells), and drug-induced acidemia. Oral form: alkalinizes urine; prevents lactic acid buildup in equine tying-up (loading dose). Key information Urinary alkalinizing compound. For oral use. Effervescent — mix with water. Monitor urine pH. Do not use in animals with edema or congestive heart failure.

IV: dilute in compatible IV fluids; Administer IV slowly; rapid infusion may cause adverse reactions. — do not mix with calcium-containing solutions in the same line. Oral (horses, alkalinization): dissolve in water; administer orally. Buffering agent in compounded IV preparations. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Metabolic alkalosis (overdose). Hyponatremia or hypernatremia (volume and concentration dependent). Hypokalemia (alkalosis shifts K+ intracellularly). Gas production: bloating/colic if given with acidic drugs. Precipitation with calcium-containing fluids. Tetany (ionized calcium reduction in alkalosis).

For animals Avoid in patients with metabolic alkalosis. Monitor pH, electrolytes, and calcium (ionized calcium decreases with alkalosis). Do not mix with calcium-containing solutions. Monitor volume status. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Alkalinizing agent — generally safe. Wash hands thoroughly with soap and water after handling. IV form: administered by veterinary staff.

Contact your veterinarian. Sodium bicarbonate overdose causes metabolic alkalosis, low calcium, and electrolyte disturbances. Managed by veterinary staff.