Cleocin Cap

Clindamycin for anaerobic bacterial infections, toxoplasmosis in cats, dental/oral infections, and osteomyelitis. Lincosamide antibiotic (clindamycin HCl). Mechanism: binds 50S ribosomal subunit → inhibits bacterial protein synthesis (bacteriostatic at low concentrations; bactericidal at high). Excellent gram-positive and anaerobic coverage; poor aerobic gram-negative activity. High tissue and bone penetration. Risk of antibiotic-associated colitis (Clostridioides). Key information Clindamycin — see clindamycin entry. Do NOT use in rabbits or hindgut fermenters. Capsule: swallow whole with water. Store at room temperature.

Oral capsules: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. and follow with water to prevent esophageal irritation. Do not give dry. Injectable: IV (dilute; infuse over 60 min) or IM. Topical: apply thin layer to affected area. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Complete the full antibiotic course.

GI: vomiting, diarrhea (most common). Antibiotic-associated colitis (Clostridioides difficile) — especially in dogs/cats; also FATAL in horses, rabbits, guinea pigs, hamsters — contraindicated in these species. Esophageal irritation (capsules without water). Rare: hepatotoxicity.

For animals CONTRAINDICATED in horses, rabbits, guinea pigs, hamsters, gerbils, and ruminants — fatal antibiotic-associated enterocolitis (Clostridium overgrowth). Use with extreme caution in dogs and cats with GI disease. Use with caution in hepatic impairment. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Lincosamide antibiotic — Wash hands thoroughly with soap and water after handling. after handling. Can cause severe Clostridioides colitis if inadvertently ingested. Contact Poison Control if swallowed.

Contact your veterinarian. Clindamycin overdose causes severe GI signs. Dangerous in rabbits/guinea pigs/hamsters.