Clevor Ophthalmic Solution
General Drug Information and Indications
Ophthalmic ropinirole for induction of emesis in dogs; selective D2/D3 receptor agonist; no physical restraint required.
Ophthalmic dopamine agonist emetic (ropinirole). Mechanism: selective D2/D3 dopamine receptor agonist in the chemoreceptor trigger zone (CTZ) in the area postrema → triggers emesis in dogs without requiring systemic absorption. Ocular administration avoids systemic adverse effects. Onset: 15–30 min. Useful alternative to apomorphine.
Key information
Ropinirole ophthalmic emesis-inducing solution for dogs. For ocular instillation only — induces vomiting via dopaminergic mechanism. Refrigerate. Single-use. Do not use in cats.
How to Give this Medication
Ophthalmic (emetic): instill 1–3 drops into the conjunctival sac of one eye only. Dog should be in a sitting or standing position. Emesis typically occurs within 15–30 min. Have bucket/emesis basin available. Administer in a calm environment. Single-use vial — discard unused portion. Store refrigerated (2–8°C); do not freeze.
If a dose is missed
This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.
Side Effects
GI: hypersalivation, lethargy after vomiting. Transient conjunctival irritation (ophthalmic application site). Miosis possible. Cardiovascular: mild bradycardia. Generally rapid and limited in adverse effects as intended single-dose emetic.
Precautions
For animals
Dogs only — not for use in cats. Do not use if the animal has ingested caustic substances, is obtunded, seizing, or has megaesophagus. Ensure adequate positioning post-emesis to prevent aspiration. Not approved for use in food-producing animals.
For people handling this medication
Wash hands thoroughly with soap and water after handling. Ophthalmic emetic — Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Avoid contact with eyes. Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children.
Overdose
Contact your veterinarian. Ropinirole ophthalmic overdose may cause persistent vomiting or low blood pressure.
Clevor Ophthalmic Solution dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| CLEVOR OPTHALMIC SOLUTION (30 MG/ML) (5 X 0.3ML) | 30 MG/ML | Solution | 1 | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com); FDA-approved label (Clevor, Vetoquinol)