Clindamycin Cap
Call to order(859) 281-9511General Drug Information and Indications
Clindamycin for anaerobic bacterial infections, toxoplasmosis in cats, dental and oral infections, skin/soft tissue infections, and osteomyelitis.
Lincosamide antibiotic. Mechanism: binds 50S ribosomal subunit → inhibits bacterial protein synthesis. Excellent gram-positive, anaerobic, and intracellular coverage (Toxoplasma). Good bone penetration. Avoid in rabbits and small herbivores (fatal colitis). Partially hepatically metabolized.
Key information
Do NOT use in rabbits, guinea pigs, hamsters, or other hindgut fermenters — fatal pseudomembranous colitis. Use with caution in horses — rarely used due to dysbiosis risk. Store at room temperature.
How to Give this Medication
Oral capsules/tablets: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. and follow with water (esophageal irritation risk). Compounded oral liquid: Shake well before each use. Store refrigerated (2–8°C); do not freeze. Injectable: IV (dilute; infuse over 30–60 min) or IM. Topical: apply thin layer. Store at room temperature; protect from light.
If a dose is missed
Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Complete the full antibiotic course.
Side Effects
GI: diarrhea, vomiting, esophageal stricture (oral capsules — give with water and remain upright). Antibiotic-associated colitis. CONTRAINDICATED in horses, rabbits, guinea pigs, hamsters, ruminants (fatal colitis). Rare: hepatotoxicity.
Precautions
For animals
CONTRAINDICATED in horses, rabbits, guinea pigs, hamsters, gerbils, and ruminants — fatal Clostridium-associated enterocolitis. Monitor for diarrhea in dogs and cats; discontinue if severe. Use with caution in hepatic impairment. Reduce dose or extend interval in renal impairment.
For people handling this medication
Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Lincosamide — Wash hands thoroughly with soap and water after handling. after handling. Risk of antibiotic-associated diarrhea if swallowed.
Overdose
Contact your veterinarian. Overdose causes GI signs. Do not use in rabbits or small herbivores — risk of fatal enterocolitis. Contact your veterinarian, a veterinary emergency clinic, or the ASPCA Animal Poison Control Center (888-426-4435) immediately. Do not induce vomiting unless specifically directed by a veterinary professional.
Clindamycin Cap dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| CLINDAMYCIN CAP 300MG | 300 MG | Capsule | — | Commercial |
| CLINDAMYCIN CAP 300MG | 300 MG | Capsule | — | Commercial |
| CLINDAMYCIN HCL CAPS 300MG | 300MG | Capsule | — | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)