Diclazuril

Anticoccidial for prevention/treatment of Sarcocystis neurona (EPM) and coccidiosis in foals. Benzeneacetonitrile anticoccidial (triazinone class). Mechanism: exact mechanism incompletely understood; disrupts intracellular organelle development in Apicomplexa protozoans (Sarcocystis, Eimeria) by affecting nuclear division and schizont development. Effective against multiple life stages of Sarcocystis neurona. Daily dosing required. Key information Store at room temperature. Antiprotozoal for EPM in horses. Complete full course. No withdrawal time established — not for use in food animals.

Oral pellets (Protazil/Marquis equivalent): weigh and administer daily. Mix into a small amount of palatable feed; ensure complete consumption. Administer at the same time each day. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Complete the full course.

Generally well tolerated. GI: mild anorexia, soft feces. Long-term safety data limited. No significant adverse effects reported at labeled doses in horses and foals.

For animals Daily dosing required — do not miss doses (compliance critical for EPM treatment). Safety in pregnant mares established at labeled doses. Not approved for use in food-producing animals. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Antiprotozoal — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact.

Contact your veterinarian. Diclazuril overdose causes mild GI signs.