Drontal Plus Tablet Chewable Large Dog
General Drug Information and Indications
Broad-spectrum antiparasitic (pyrantel/praziquantel/febantel) for roundworms, hookworms, tapeworms, and whipworms in dogs and cats.
Combination anthelmintic (praziquantel + pyrantel pamoate ± febantel). Praziquantel: disrupts cestode tegument via calcium channel-mediated muscle hypercontraction; pyrantel: nicotinic acetylcholine receptor agonist causing depolarizing neuromuscular blockade in nematodes; febantel: pro-drug converted to fenbendazole (tubulin inhibitor). Broad-spectrum combination.
Key information
Praziquantel/pyrantel combination. Store at room temperature. No food restriction required. Safe in pregnant animals. Effective against tapeworms and roundworms.
How to Give this Medication
Oral tablets: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. or without. Scored tablets may be split for dose adjustment. Administer appropriate weight-based tablet. Store at room temperature; protect from light.
If a dose is missed
This product is given as a single dose or as part of a defined protocol. Contact your veterinarian if a scheduled administration was missed.
Side Effects
GI: transient vomiting, diarrhea, salivation, anorexia (self-limiting). Neurological signs at very high overdoses (pyrantel toxicity). Generally well tolerated at labeled doses.
Precautions
For animals
Generally safe at labeled doses. Confirm adequate GI motility before dosing. Not for use in animals with known hypersensitivity to praziquantel or pyrantel.
For people handling this medication
Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Anthelmintic combination — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children.
Overdose
Contact your veterinarian. Praziquantel/pyrantel overdose may cause salivation, vomiting, diarrhea, and ataxia. Contact your veterinarian, a veterinary emergency clinic, or the ASPCA Animal Poison Control Center (888-426-4435) immediately. Do not induce vomiting unless specifically directed by a veterinary professional.
Drontal Plus Tablet Chewable Large Dog dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| DRONTAL PLUS CHEWABLE MEDIUM DOG TAB | — | Tablet | 1 | Commercial |
| DRONTAL PLUS CHEWABLE SMALL DOG TAB | — | Tablet | 1 | Commercial |
| DRONTAL PLUS TABLET CHEWABLE LARGE DOG | — | Tablet | 1 | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)