Enoxaparin Inj 300/3ml

Low-molecular-weight heparin for prevention and treatment of thromboembolic disease in cats and dogs. Low-molecular-weight heparin (LMWH — enoxaparin sodium). Mechanism: binds antithrombin III → potentiates inhibition of Factor Xa (primarily) and thrombin → anticoagulant effect. Predictable pharmacokinetics; subcutaneous bioavailability ~92%. Less monitoring needed than unfractionated heparin. Renally cleared; caution in renal impairment. Key information Refrigerate. Subcutaneous injection only. Do not aspirate before injection. Low molecular weight heparin — anti-Xa monitoring available. Incompatible with other drugs in same syringe. Dose adjustment in renal impairment.

SQ injection: administer SQ (never IM or IV bolus). Pinch skin into a fold; inject into abdominal or lateral thoracic skin fold. Alternate sides for repeat doses. Do not expel air bubble from pre-filled syringe before injection. Store refrigerated (2–8°C); do not freeze. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Enoxaparin is given once or twice daily — consistency is important for anticoagulation. Contact your veterinarian if you are unsure about timing.

Hemorrhage: hematoma at injection site, internal bleeding. Thrombocytopenia (HIT — less common with LMWH than UFH). Pain/bruising at SQ injection site. Hyperkalemia. Overdose: no specific antidote (partially reversed by protamine).

For animals Reduce dose or extend interval in renal impairment. — dose-reduce in renal impairment. Monitor anti-Xa activity if available. No fully effective reversal agent (protamine partially reverses). Avoid in patients with active major bleeding. Use with caution in pregnant animals. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Anticoagulant injectable — risk of bleeding if accidentally self-injected. If accidental injection occurs, seek medical attention. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact.

Contact your veterinarian immediately. Signs of overdose include abnormal bleeding, pale gums, or sudden weakness. Protamine sulfate may partially reverse the effect; supportive care will be needed.