Entederm, Gentamicin & Malic/benzoic/salicylic Acid

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General Drug Information and Indications

Topical otic/dermatologic combination (nystatin/neomycin/thiostrepton/triamcinolone) for otitis externa and skin infections. Topical otic combination: nystatin (polyene antifungal), neomycin sulfate (aminoglycoside antibacterial), thiostrepton (polycyclic antibacterial), and triamcinolone acetonide (fluorinated corticosteroid). Provides comprehensive antifungal, antibacterial, and anti-inflammatory coverage for otitis externa and infected dermatoses. Key information Multi-drug otic/topical combination. Shake well. Do not use in perforated eardrum. Gentamicin component: nephrotoxic/ototoxic if systemic absorption occurs.

How to Give this Medication

Clean ear canal before instillation. Gently massage base of ear after application to distribute medication. Instill prescribed number of drops into ear canal. Massage base of ear. Apply 2–3 times daily. Verify TM integrity before otic use. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

Otic: local irritation. Neomycin: ototoxicity with ruptured tympanum — verify TM integrity. Triamcinolone: adrenal suppression with prolonged use. Generally well tolerated for labeled otic use.

Precautions

For animals Verify tympanic membrane integrity before otic use — neomycin is ototoxic with ruptured TM. Triamcinolone: adrenal suppression with prolonged use, especially in small dogs/cats. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Otic combination — wear gloves. Contains neomycin (allergen) and triamcinolone. Avoid ear exposure. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention.

Overdose

Contact your veterinarian immediately. Gentamicin overdose causes acute kidney failure and irreversible hearing loss. IV fluid support required urgently. Medical emergency.

Entederm, Gentamicin & Malic/benzoic/salicylic Acid dosage forms

ProductStrengthFormSizeType
ENTEDERM(ANIMAX), GENTAMICIN & MALIC/BENZOIC/SALICYLIC ACID 7%, 0.2%, 5%/1%/1% OINTMENT7%, 0.2%, 5%/1%/1%Ointment1Compound

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)