Epinephrine Injectable

Emergency treatment of anaphylaxis and severe allergic reactions; cardiac resuscitation; bronchodilation; hemostasis. Endogenous catecholamine (epinephrine / adrenaline). Mechanism: non-selective alpha and beta adrenergic receptor agonist. Alpha-1: peripheral vasoconstriction → raises BP. Beta-1: positive chronotropy/inotropy → increases CO. Beta-2: bronchodilation and inhibits mast cell degranulation. First-line drug for anaphylaxis and cardiac arrest. Endogenous fight-or-flight hormone. Key information Life-saving drug — keep immediately accessible for anaphylaxis. Refrigerate or store at room temperature per product insert. Protect from light. Discard if solution is discolored or contains particulate. Never mix in same syringe as sodium bicarbonate (inactivated). IM preferred over SC for anaphylaxis treatment.

IV (emergency): administer as rapid IV bolus (dilute 1:10,000 for IV). IM (anaphylaxis): administer into large muscle mass (lateral thigh preferred for rapid absorption). Intratracheal (if no IV access): dilute and instill. Monitor ECG during administration. Store at room temperature; protect from light. Protect from light. Single-use ampules/vials. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Cardiovascular: tachycardia, hypertension, arrhythmias (PVCs, VT), myocardial infarction (high doses). CNS: anxiety, tremors, headache. Tissue necrosis with extravasation. Hyperglycemia. Pulmonary edema (high doses). Cerebral hemorrhage (hypertension).

For animals Drug interaction: do not use with halogenated anesthetic agents — risk of sensitization and fatal ventricular arrhythmias. Avoid in patients with hypertrophic obstructive cardiomyopathy (increases dynamic obstruction). Use lowest effective dose. For people handling this medication Wear gloves when handling. Potent vasoconstrictor/cardiac stimulant. If accidentally self-injected (including from auto-injector), seek emergency medical attention immediately even if you feel fine — can cause severe hypertension and cardiac arrhythmias. Keep out of reach of children.

Contact your veterinarian. Epinephrine overdose causes rapid heart rate, severe hypertension, cardiac arrhythmias, and anxiety. Medical emergency requiring cardiac monitoring.