Equizone 50
General Drug Information and Indications
Oxibendazole-based anthelmintic for control of intestinal parasites including strongyles, roundworms, and pinworms in horses.
Benzimidazole anthelmintic (oxibendazole). Mechanism: binds beta-tubulin → inhibits tubulin polymerization and microtubule assembly → impairs parasite glucose uptake and cellular division → death of susceptible helminths. Active against small strongyles (cyathostomes), large strongyles, roundworms (Parascaris), and pinworms.
Key information
Omeprazole oral paste/granules for horses. Store at room temperature. Administer on empty stomach 30–60 min before feeding. Full course required for active ulcers.
How to Give this Medication
Oral paste: Administer orally via dose syringe placed at the back of the tongue, or mix into a small amount of palatable feed. via dose syringe at appropriate weight marking. Administer as a single dose. Store at room temperature; protect from light.
If a dose is missed
Give the missed dose as soon as you remember, on an empty stomach. Do not double up.
Side Effects
GI: anorexia, vomiting, diarrhea. GI discomfort at high doses. Hepatotoxicity (rare with benzimidazoles). Superinfection with resistant parasites.
Precautions
For animals
Monitor liver enzymes with prolonged use. Not approved for use in food-producing animals. Resistance can develop — perform fecal egg count reduction testing to confirm efficacy. Use with caution in pregnant animals.
For people handling this medication
Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Benzimidazole anthelmintic — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact.
Overdose
Contact your veterinarian. Omeprazole overdose causes GI signs.
Equizone 50 dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| EQUIZONE 1GM/10GM POWDER 100 GM | 10 GM | Powder | 1 | Commercial |
| EQUIZONE 1GM/10GM POWDER 50 GM | 10 GM | Powder | — | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)