Etodolac Tabs

COX-2 preferential NSAID for musculoskeletal pain and inflammation in dogs; management of osteoarthritis. COX-2 preferential NSAID (etodolac). Mechanism: preferentially inhibits COX-2 over COX-1 → reduced prostaglandin synthesis at inflammatory sites. Indole-acetic acid derivative. Oral tablets for dogs. GI safety improved vs. non-selective NSAIDs. Hepatically metabolized. Key information NSAID — do not use in cats. Dogs only. Administer with food. Do not combine with other NSAIDs or corticosteroids. Monitor renal function. Keratoconjunctivitis sicca (KCS) reported — monitor tear production with prolonged use.

Oral tablets: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. Administer once daily. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one.

GI: vomiting, diarrhea, gastric ulceration. Renal toxicity with dehydration. Hepatotoxicity (monitor enzymes). KCS (dry eye) in dogs (reported). Do not combine with other NSAIDs.

For animals Monitor for GI ulceration; use with caution in animals with GI disease. Monitor renal function, hydration status, and urine output. Monitor liver enzymes with prolonged use. Do not use concurrently with other NSAIDs or corticosteroids. Monitor for KCS in dogs with prolonged use. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). NSAID — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children.

Contact your veterinarian immediately. Overdose causes GI ulceration, kidney injury, and may affect tear production (KCS). Supportive care required.