Excede

General Drug Information and Indications

Extended-release ceftiofur injectable for equine respiratory disease and lower respiratory infections. Extended-release ceftiofur injectable (ceftiofur crystalline free acid). Mechanism: third-generation cephalosporin binds PBPs → inhibits cell wall synthesis (bactericidal). Crystalline free acid suspension in sesame oil provides sustained drug release for 7–14 days after IM/SQ injection at base of ear. Indicated for equine and bovine respiratory disease. Key information Ceftiofur crystalline free acid (CCFA). Long-acting injectable cephalosporin. Shake vigorously before use. Subcutaneous injection at base of ear in cattle. Beef withdrawal: 13 days (SC). Dairy cattle: 13 days after last treatment. Do not use in calves to be processed as veal.

How to Give this Medication

IM or SQ injection (cattle, swine): shake vigorously before use. Horses: administer SQ at the base of the ear (right side for initial dose, left for repeat if needed). Maximum volume per injection site: 15 mL (horses), 10 mL (cattle). Warm vial slightly for easier injection. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

Injection site reactions (pain, swelling, edema — often significant at ear base injection site; residue lump may persist). Hypersensitivity reactions (rare). GI: diarrhea. Withdrawal times apply (food animals).

Precautions

For animals Observe food animal withdrawal times for milk and meat. Not for use in horses intended for human consumption. Local tissue reaction at injection site (ear base) is expected and may persist — inform owners. Aseptic technique required. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Extended-release cephalosporin injectable — inform your doctor if you have beta-lactam allergy. Injectable — administered by veterinary staff only. Wash hands thoroughly with soap and water after handling. If accidentally self-injected, seek emergency medical attention immediately. Wear gloves.

Overdose

Contact your veterinarian. This is a long-acting injectable — dosing is managed by veterinary staff.

Excede dosage forms

ProductStrengthFormSizeType
EXCEDE INJ 100ML 200 MG/ML INJ SUSP200 MG/MLInjectable1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)