Firocoxib Tablets 57 mg

COX-2 selective NSAID (Previcox/Equioxx) for osteoarthritis pain in dogs and horses. Highly COX-2 selective NSAID (firocoxib). Mechanism: >300:1 selectivity for COX-2 inhibition vs. COX-1 → marked reduction in inflammatory prostaglandin production with minimal effect on constitutive COX-1 prostaglandins protecting gastric mucosa and supporting platelet function. Approved for dogs (Previcox) and horses (Equioxx). Once-daily dosing. Key information COX-2 selective NSAID (Equioxx/Previcox). Not for use in horses intended for human consumption. Horses: paste formulation; dogs: chewable tablet. Administer with food in dogs. Do not combine with other NSAIDs or corticosteroids.

Oral paste (horses — Equioxx): administer via dose syringe into the back of the mouth. Once daily. Oral chewable tablets (dogs — Previcox): Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. Once daily. Injectable (horses): administer IV only — slowly. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember. If the next dose is due within a few hours, skip the missed dose and resume the regular schedule. Never give a double dose.

GI: gastric/colonic ulceration (lower than non-selective NSAIDs — COX-2 selectivity), vomiting, diarrhea, anorexia (dogs). Renal: azotemia with dehydration or pre-existing CKD. Hepatotoxicity (monitor enzymes at baseline). Do not combine with other NSAIDs or steroids.

For animals Horses and dogs only. Monitor for GI ulceration; use with caution in animals with GI disease. Monitor renal function, hydration status, and urine output. Monitor liver enzymes with prolonged use. Do not use concurrently with other NSAIDs or corticosteroids. Baseline and periodic monitoring of renal function and liver enzymes. Use with caution in pregnant animals. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). COX-2 NSAID — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children.

Contact your veterinarian or emergency clinic immediately. Overdose causes GI ulceration and kidney injury in horses and dogs. Do not give additional doses.