General Drug Information and Indications

Potent topical corticosteroid for inflammatory skin conditions and otitis externa. Potent halogenated topical corticosteroid (fluocinonide). Mechanism: binds glucocorticoid receptors in skin → inhibits phospholipase A2, reduces cytokine transcription → potent local anti-inflammatory, antipruritic, and vasoconstrictive effects. Group II potency corticosteroid; significant systemic absorption with prolonged use over large areas. Key information Topical corticosteroid. For external use only. Avoid large surface areas. Systemic absorption possible. Do not use near eyes.

How to Give this Medication

Apply topically to affected area; wear gloves during application. Apply thin layer to affected skin 2–3 times daily. Do not cover with occlusive bandage unless directed. Avoid eyes and mucous membranes. Wear gloves during application. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Side Effects

HPA axis suppression (significant with large-area or prolonged application). Skin atrophy, telangiectasia, striae with chronic use. Impaired wound healing. Acneiform eruptions. Steroid rosacea. Systemic effects with occlusive use.

Precautions

For animals Do not use on large areas for prolonged periods — HPA suppression. Avoid on thin-skinned or damaged areas. Avoid in pregnant animals. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Potent topical corticosteroid — wear gloves to avoid skin contact. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Minimize application area and duration.

Overdose

If excessive product was applied, wash the area thoroughly with mild soap and water. Contact your veterinarian if the animal shows any signs of irritation, lethargy, tremors, or other unusual behavior. Potent topical corticosteroid — systemic absorption possible. Contact your veterinarian.

Fluocinonide Sol dosage forms

ProductStrengthFormSizeType
FLUOCINONIDE SOL 0.05%——1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Corticosteroids in Animals (https://www.merckvetmanual.com/pharmacology/inflammation/corticosteroids-in-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)