Flurbiprofen
General Drug Information and Indications
Topical NSAID ophthalmic drops for pre-operative miosis inhibition and ocular inflammation.
Propionic acid NSAID (flurbiprofen). Mechanism: non-selective COX inhibitor → reduces prostaglandin synthesis in ocular tissues. Available as 0.03% ophthalmic solution. Inhibits surgically induced miosis; reduces post-operative ocular inflammation.
Key information
Ophthalmic NSAID. For ophthalmic use only. Contains thimerosal in some formulations. Do not use in animals with corneal ulcer.
How to Give this Medication
Ophthalmic solution: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. Instill 1 drop into affected eye(s) as directed. Store at room temperature; protect from light.
If a dose is missed
Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.
Side Effects
Ophthalmic: mild transient burning, stinging. Superficial punctate keratopathy. Potential to slow corneal epithelial wound healing (COX inhibition). Systemic absorption minimal.
Precautions
For animals
Topical ophthalmic — not for injection. Do not use concurrently with other NSAIDs or corticosteroids. May delay corneal epithelial wound healing.
For people handling this medication
Wash hands thoroughly with soap and water after handling. Ophthalmic NSAID — avoid human eye contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Wash hands thoroughly with soap and water after handling. after use.
Overdose
Contact your veterinarian if eye irritation occurs. Ophthalmic NSAID — systemic toxicity from eye drops is unlikely.
Flurbiprofen dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| FLURBIPROFEN 0.03% OPTH SOL | — | — | 1 | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Nonsteroidal Anti-inflammatory Drugs in Animals (https://www.merckvetmanual.com/pharmacology/inflammation/nonsteroidal-anti-inflammatory-drugs-in-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)