Furosemide Tab

Loop diuretic for pulmonary edema, congestive heart failure, exercise-induced pulmonary hemorrhage (EIPH) in horses; edema and ascites in dogs and cats. Loop diuretic (furosemide). Mechanism: inhibits Na-K-2Cl cotransporter (NKCC2) in thick ascending loop of Henle → prevents reabsorption of Na+, K+, Cl- → marked diuresis. Also venodilatory effect (reduces preload acutely). Powerful short-acting diuretic. Used for EIPH in horses: reduces pulmonary blood pressure/volume pre-exercise. Sulfonamide-derived. Key information Loop diuretic. Monitor electrolytes (hypokalemia, hyponatremia). Potentiates aminoglycoside nephrotoxicity and ototoxicity — avoid concurrent use. Dehydration risk. Store at room temperature. USEF withdrawal time: consult current rules.

IV: administer slowly (over 1–2 min); rapid IV bolus can cause ototoxicity. IM or SQ: inject into large muscle mass. Oral tablets or solution: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. or without. Horses (EIPH): administer IV 4 hrs before racing per regulatory requirements. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember. If the next dose is due within a few hours, skip the missed dose and resume the regular schedule. Never give a double dose.

Electrolyte imbalances: hypokalemia, hyponatremia, hypomagnesemia, hypochloremic metabolic alkalosis (most common — monitor electrolytes). Dehydration, prerenal azotemia with excessive diuresis. Ototoxicity with high doses or rapid IV injection. Hypercalciuria. GI: vomiting, anorexia. Thiamine depletion with prolonged use.

For animals Monitor electrolytes (K+, Na+, Mg2+) and hydration. Hypokalemia risk — supplement potassium if needed. Ototoxicity with high doses or rapid IV infusion. Drug interaction: aminoglycosides (additive nephrotoxicity), NSAIDs (reduce diuretic effect). Horses: avoid over-diuresis before competition — compromises performance and health. Use with caution in pregnant animals. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Loop diuretic — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children. Sulfonamide derivative — inform doctor if sulfa-allergic.

Contact your veterinarian. Furosemide overdose causes dehydration, electrolyte loss, and kidney stress.