Hetastarch Inj

Synthetic colloid for volume replacement and oncotic support in horses and small animals with hypoproteinemia and shock. Synthetic colloid volume expander (hydroxyethyl starch / HES). Mechanism: large polysaccharide molecules (MW 200–450 kDa) remain in intravascular space → maintain oncotic pressure and plasma volume expansion. Reduces capillary leak in endotoxemia. Maximum dose-dependent coagulopathy risk; use with caution in horses. Key information Colloid solution. Store at room temperature. Limit to 20 mL/kg/day in dogs and cats. Monitor for coagulopathy with high doses. Do not use in animals with coagulopathy or oliguria. Discard unused portion — single use.

IV infusion: administer via IV catheter as CRI or bolus over 15–30 min. Do not exceed recommended maximum daily dose. Monitor patient response (urine output, blood pressure, mucosal membrane color). Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Coagulopathy: dose-dependent decrease in Factor VIII and von Willebrand factor, prolonged PT/aPTT. Acute kidney injury (rare — controversial; avoid in renal insufficiency). Volume overload/pulmonary edema with excessive doses. Pruritus (delayed hypersensitivity). Anaphylaxis (rare).

For animals Maximum dose limits to reduce coagulopathy risk (typically ≤20 mL/kg/day in dogs/cats). Monitor coagulation parameters with repeated dosing. Use with caution or avoid in patients with coagulopathy, renal failure, or severe anemia. Not approved for use in food-producing animals. For people handling this medication Administered by veterinary professionals only. No specific human precautions for caregivers beyond normal hygiene. IV colloid administered by veterinary staff.

Contact your veterinarian. Hetastarch overdose causes coagulopathy and fluid overload. Managed by veterinary staff.