Higamma-equi 1000ml Injectable

Equine hyperimmune plasma for passive immunization and treatment of neonatal foal immunodeficiency, septicemia, and failure of passive transfer. Equine hyperimmune plasma. Mechanism: contains high titers of specific antibodies (IgG) harvested from donor horses immunized against common equine pathogens (Rhodococcus equi, gram-negative organisms, endotoxin). IV administration provides passive immunization — immediate but temporary protection (weeks). Also provides complement, fibronectin, and other plasma proteins. Key information Equine plasma (hyperimmune) IV. Refrigerate; check expiry. Warm to body temperature before IV infusion. Use IV administration set with filter. Monitor for transfusion reactions (fever, urticaria).

IV infusion: administer through a sterile IV administration set with filter. Infuse slowly (begin at 0.5 mL/kg/hr; increase to 2 mL/kg/hr if no reaction after 15 min). Monitor patient continuously for transfusion reactions during infusion. Store refrigerated (2–8°C); do not freeze. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Volume overload/pulmonary edema (especially in foals with compromised cardiovascular function). Transfusion reactions: fever, urticaria, hemolysis (from alloantibodies). Johne's disease transmission risk with biosecurity-unverified plasma. Disease transmission (biosecurity-screened donors minimize risk).

For animals Administer IV slowly (over 30–60 min); monitor for transfusion reactions (fever, urticaria, edema). Have epinephrine available. Foals: volume overload risk — do not exceed recommended volume per dose. Cross-match if available. Disease transmission risk — use biosecurity-screened products. For people handling this medication Administered by veterinary professionals only. No specific human precautions for caregivers beyond normal hygiene.

Contact your veterinarian. Hyperimmune plasma transfusion reactions (fever, urticaria, anaphylaxis) are managed by veterinary staff.