General Drug Information and Indications

Topical hydrocortisone cream for mild inflammatory skin conditions in dogs and cats. Low-potency topical corticosteroid (hydrocortisone 0.5–2.5% cream). Mechanism: glucocorticoid receptor agonist → reduces keratinocyte cytokine and prostaglandin production → mild anti-inflammatory and antipruritic effects. Least potent topical corticosteroid class. Minimal systemic absorption at standard concentrations over intact skin. Key information Hydrocortisone cream — mild topical corticosteroid. See hydrocortisone entry. For external use only.

How to Give this Medication

Topical cream: apply thin layer to affected skin 2–4 times daily. Rub gently until absorbed. Avoid eyes and mucous membranes. Wear gloves. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Side Effects

Low-potency topical: generally well tolerated. Skin atrophy with prolonged use over large areas. HPA suppression with widespread or occluded application. Impaired wound healing. Acneiform eruptions.

Precautions

For animals Topical: minimal HPA suppression at low potency with appropriate use. Avoid prolonged use on large areas or under occlusion. Use with caution in pregnant animals. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Low-potency topical corticosteroid — wear gloves to avoid skin absorption. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Minimize prolonged skin contact.

Overdose

If excessive product was applied, wash the area thoroughly with mild soap and water. Contact your veterinarian if the animal shows any signs of irritation, lethargy, tremors, or other unusual behavior. Mild topical corticosteroid — systemic effects unlikely with normal use. Contact veterinarian if large areas were treated repeatedly.

Hydrocort Cre dosage forms

ProductStrengthFormSizeType
HYDROCORTISONE CREAM 2.5%——1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Corticosteroids in Animals (https://www.merckvetmanual.com/pharmacology/inflammation/corticosteroids-in-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)