Imiquimod Cre

Topical immune response modifier for treatment of equine sarcoids, papillomas, and other neoplasms; stimulates local innate and adaptive immunity. Toll-like receptor (TLR) agonist immune response modifier (imiquimod 5% cream). Mechanism: binds TLR7/TLR8 on plasmacytoid dendritic cells and macrophages → NFκB activation → induction of pro-inflammatory cytokines (IFN-α, IFN-γ, TNF-α, IL-6, IL-12) → stimulates innate and adaptive anti-tumor immunity. Topical application induces local regression of neoplastic lesions. Key information Topical immune modulator. Apply thin layer only — systemic absorption possible. Causes local inflammation (expected). Wear gloves. Do not apply near eyes or mucous membranes.

Topical cream: Apply topically to affected area; wear gloves during application. Apply thin layer to target lesion(s) using gloved fingers 3 times weekly or as directed. Leave in contact for prescribed duration. Do not bandage treated area. Wash hands thoroughly after application. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Local: erythema, erosion, ulceration, crusting, scabbing, pain at application site (common, expected inflammatory reaction). Flu-like symptoms (fatigue, fever, headache, myalgia) — immune system activation. Rarely systemic (due to minimal absorption). Wear gloves when applying.

For animals Topical use only — not for injection or ingestion. Apply with gloves. Avoid in pregnant animals. Local reaction is expected and indicates immune activation. Do not use on large areas. For people handling this medication Wear gloves when handling. Immune modifier — wear gloves when applying. Avoid contact with own skin and mucous membranes. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Wash hands immediately after application.

Contact your veterinarian. Imiquimod overdose causes local inflammation and systemic flu-like signs with excessive use. Wear gloves.