Iodine/dmso/camphor
General Drug Information and Indications
Compounded topical iodine in DMSO vehicle for enhanced penetration; treatment of fungal infections, wound antisepsis, and soft tissue conditions in horses.
Halogen antiseptic (iodine/iodophor solutions). Mechanism: elemental iodine rapidly penetrates microbial cell walls → oxidizes and iodinates cellular proteins and nucleic acids → cell death. Broad-spectrum: bacteria (including spores), fungi, viruses, protozoa. Lugol's solution (5% I2 + 10% KI): concentrated iodine for uterine infusion, wound cauterization.
Key information
HUMAN SAFETY: DMSO carrier — wear chemical-resistant gloves. Topical only. Camphor component: toxic if ingested in quantity. External use only.
How to Give this Medication
Topical wound use: dilute to 0.1–1% before applying to wounds. Full-strength Lugol's (5%) is caustic — do not apply directly to wound tissue. Apply via syringe or gauze. Intrauterine (mares): dilute Lugol's to 1–2% in sterile saline; infuse via sterile catheter using aseptic technique. Store at room temperature; protect from light. Protect from light.
If a dose is missed
Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.
Side Effects
Irritant/caustic at high concentrations (tissue damage, delayed wound healing — do not use >1% on wounds). Iodine toxicity: excessive systemic absorption from large wounds. Thyroid hormone dysregulation. Staining (expected). Hypersensitivity (iodine allergy).
Precautions
For animals
Use only appropriately diluted solutions on wounds — full-strength Lugol's (5%) is caustic and cytotoxic to healing tissue. Dilute to 0.1–1% for wound use. Intrauterine Lugol's: dilute to 1–2% for mares.
For people handling this medication
Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Iodine solutions — can stain skin and clothing. Caustic at high concentrations. Wear gloves. Eye contact: flush immediately. Keep out of reach of children.
Overdose
Contact your veterinarian. Topical iodine overdose causes local tissue damage. If significant iodine is ingested or absorbed, iodism signs (excessive salivation, nasal discharge, skin rash) may develop.
Iodine/dmso/camphor dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| IODINE/DMSO/CAMPHOR 45%TRIODINE 7/45%/1.6% LEG PAINT | 45%TRIODINE 7/45%/1.6% LEG PAINT | Liquid | 1 | Compound |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Compounding pharmacy formulation; Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)