Isoflupredone Acetate & Zinc Oxide In Miracle Heel

Potent fluorinated corticosteroid used topically and systemically in horses and cattle for anti-inflammatory therapy. Potent fluorinated corticosteroid (isoflupredone acetate). Mechanism: glucocorticoid receptor agonist with moderate mineralocorticoid activity → anti-inflammatory via phospholipase A2 inhibition. 9α-fluoro, 16α-methyl substituted prednisolone derivative. Approximately 10× more potent than cortisol. Administered IM or topically (in DMSO preparations). Risk of hypokalemia in cattle. Key information Topical hoof treatment. Wear gloves (corticosteroid + DMSO potentially present). For hoof/digital area topical use.

IM injection: administer deep IM into large muscle mass. Topical (in DMSO vehicles): apply to affected area with chemical-resistant gloves. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

All corticosteroid effects: PU/PD, muscle wasting, immunosuppression, delayed wound healing, laminitis risk (horses). Hypokalemia (significant mineralocorticoid activity — monitor potassium, especially in cattle where fatal hypokalemia reported). GI ulceration. HPA axis suppression.

For animals Monitor for GI ulceration; use with caution in animals with GI disease. Hypokalemia risk is significant, especially in cattle — monitor serum potassium, supplement as needed. Laminitis risk in horses. Avoid in pregnant animals. Do not use concurrently with other NSAIDs or corticosteroids. Avoid live vaccines. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Potent corticosteroid — avoid prolonged skin contact. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Wear gloves when handling.

Contact your veterinarian. Isoflupredone has potent mineralocorticoid effects — overdose causes sodium and water retention, potassium loss, and muscle weakness.