Isoflupredone/dmso Leg Paint

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General Drug Information and Indications

Compounded topical leg paint combining isoflupredone (corticosteroid) with DMSO vehicle for anti-inflammatory treatment of soft tissue and joint conditions in horses. Compounded leg paint combining isoflupredone acetate (potent fluorinated corticosteroid — anti-inflammatory) with DMSO (penetration-enhancing solvent/anti-inflammatory carrier). Applied topically to inflamed lower limbs in horses. Key information HUMAN SAFETY: DMSO carrier — wear chemical-resistant gloves. Isoflupredone has potent mineralocorticoid effects — monitor electrolytes. Topical use only.

How to Give this Medication

IM injection: administer deep IM into large muscle mass. Topical (in DMSO vehicles): apply to affected area with chemical-resistant gloves. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

Same as DMSO/isoflupredone. Significant systemic corticosteroid absorption via DMSO carrier — monitor for laminitis, HPA suppression, hypokalemia, immunosuppression.

Precautions

For animals Monitor for GI ulceration; use with caution in animals with GI disease. Hypokalemia risk is significant, especially in cattle — monitor serum potassium, supplement as needed. Laminitis risk in horses. Avoid in pregnant animals. Do not use concurrently with other NSAIDs or corticosteroids. Avoid live vaccines. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Potent corticosteroid — avoid prolonged skin contact. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Wear gloves when handling.

Overdose

Contact your veterinarian. Isoflupredone has potent mineralocorticoid effects — overdose causes sodium and water retention, potassium loss, and muscle weakness.

Isoflupredone/dmso Leg Paint dosage forms

ProductStrengthFormSizeType
ISOFLUPREDONE/DMSO LEG PAINT 0.06MG/ML SOLUTION0.06 MG/MLSolution1Compound

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Compounding pharmacy formulation; Merck Veterinary Manual – Corticosteroids in Animals (https://www.merckvetmanual.com/pharmacology/inflammation/corticosteroids-in-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)