Kenalog-10 (5ml)

Triamcinolone acetonide long-acting injectable for intra-articular equine joint inflammation; intralesional injection for skin lesions. Long-acting injectable triamcinolone acetonide. Mechanism: potent fluorinated glucocorticoid receptor agonist → transcriptional inhibition of inflammatory mediator genes via NF-κB suppression; induces annexin-1 → phospholipase A2 inhibition. Acetonide ester provides depot effect with sustained release from injection site (3–4 weeks). No mineralocorticoid activity. Key information Triamcinolone acetonide depot — long-acting corticosteroid. Potent and long-lasting HPA suppression. Do not inject intravenously. Use with caution in animals with diabetes or Cushing's disease. Competition withdrawal required.

IM: administer deep IM into large muscle mass. Intra-articular: strict aseptic technique — clip, prep, and dry site; aspirate joint fluid before injecting. Intralesional: inject directly into lesion (sarcoids, granulomas) using aseptic technique. Restrict exercise 24–48 hrs after intra-articular injection. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

HPA axis suppression, laminitis (horses), PU/PD/PP, immunosuppression, delayed wound healing, muscle wasting, GI ulceration. Intra-articular: post-injection flare (24–72 hrs), cartilage damage with repeated use, septic arthritis risk. Crystal-induced synovitis.

For animals Intra-articular: aseptic technique essential; limit to max 3–4 injections/year per site. Monitor for GI ulceration; use with caution in animals with GI disease. Laminitis risk in horses (especially at-risk patients). Avoid in pregnant animals. Adrenal suppression — monitor with repeated use. Do not use concurrently with other NSAIDs or corticosteroids. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Potent corticosteroid injectable — Injectable — administered by veterinary staff only. Wash hands thoroughly with soap and water after handling. If accidentally self-injected, seek emergency medical attention immediately. Wear gloves. Avoid prolonged skin contact. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact.

Contact your veterinarian. Triamcinolone depot injection overdose causes prolonged immunosuppression and metabolic effects. Signs include PU/PD, muscle wasting, and vulnerability to infection.