Lime Sulfur

General Drug Information and Indications

Topical antifungal/antiparasitic for dermatophytosis, Sarcoptes, Cheyletiella, and Demodex in horses and small animals. Calcium polysulfide antifungal/antiparasitic solution. Mechanism: sulfide ions (S2-) and elemental sulfur penetrate keratinized structures; act as reducing agents disrupting microbial disulfide bonds in structural proteins; direct contact toxicity to fungal cells, mite cuticles, and keratinocyte-embedded organisms. Keratolytic effects aid penetration. Key information Topical antifungal/antiparasitic dip. Dilute per label — concentrated product corrosive. Pungent sulfur odor. Apply with gloves in well-ventilated area. Stains clothing/surfaces. Keep away from eyes.

How to Give this Medication

Topical dip: dilute 1:16 to 1:32 in warm water (approximately 60 mL per 4 L). Apply to entire body; work into coat thoroughly. Do not rinse off — allow to air dry. Use in a well-ventilated area. Apply Elizabethan collar to prevent licking (especially cats). Wear gloves and old clothing. Apply weekly until culture-negative. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Side Effects

Strong sulfur odor (objectionable — warn owners). Skin: yellow/brown discoloration, drying. Eye contact: serious chemical burn/conjunctivitis. CNS toxicity in cats if licked excessively — use Elizabethan collar after application. Skin staining. Environmental: stains fabrics, surfaces.

Precautions

For animals CONTRAINDICATED in cats if licked (CNS toxicity) — use Elizabethan collar. Use in well-ventilated area. Avoid eyes. Dilute to appropriate concentration for species and application. Not approved for use in food-producing animals. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Strong sulfur odor — use in well-ventilated area. Skin irritant; can cause chemical burns at high concentrations. Yellow staining of skin and clothing. Eye contact: flush immediately and seek medical attention. Wear gloves and old clothing.

Overdose

Contact your veterinarian. If ingested, causes severe GI irritation and possible systemic toxicity.

Lime Sulfur dosage forms

ProductStrengthFormSizeType
LIME SULFUR 6.5% SOLUTION - 1 GALLON—Solution1 GALLONCompound
LIME SULFUR 6.5% SOLUTION - 480 ML—Solution480 MLCompound

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)