Macrosyn Inj

Cloprostenol (synthetic prostaglandin) for estrus synchronization and luteolysis in mares and cattle. Synthetic prostaglandin F2α analogue (cloprostenol sodium). Mechanism: binds FP prostaglandin receptors on corpus luteum → luteolysis and progesterone decline; potent uterine smooth muscle contractor. More potent and longer-acting than natural PGF2α. Used for synchronization, luteolysis, and abortion in mares and cattle. IM injection. Key information Sodium hyaluronate IV for horses. Refrigerate. IV or intra-articular use. Strict aseptic technique. Single-use.

IM injection (horses and cattle): administer deep IM. NEVER administer IV. Wear chemical-resistant nitrile gloves. Observe horses for 60 min post-injection for adverse reactions. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

GI: abdominal cramping, diarrhea. Sweating, restlessness, tachycardia (horses — transient within 1 hr). Abortion (any pregnant animal). Do not administer IV. Human contact hazard (reproductive/cardiovascular effects — use gloves).

For animals See cloprostenol. Avoid in pregnant animals. Do not administer IV. Monitor for adverse reactions 1 hr post-dose. IM/SQ only. For people handling this medication SERIOUS HUMAN HAZARD: Cloprostenol is readily absorbed through skin and causes serious reproductive harm. Pregnant women and women of childbearing age must NOT handle — can cause abortion or premature labor. Wear chemical-resistant (nitrile) gloves and protective clothing. If skin contact occurs, wash immediately. If eye contact occurs, flush for 15+ minutes and seek medical attention. Keep out of reach of children.

Contact your veterinarian. HA IV/IA product — overdose managed by veterinary staff.