Meclizine Tab

Antihistamine/antiemetic for vestibular disease-associated nausea and vertigo in dogs and cats. First-generation antihistamine/antiemetic (meclizine HCl). Mechanism: H1 histamine receptor antagonist with anticholinergic and CNS depressant properties. Antiemetic effect via blockade of H1 receptors in vestibular nuclei and vomiting center. Used for vestibular syndrome (motion sickness, idiopathic vestibular disease). Oral tablets. Key information Antihistamine antiemetic for motion sickness/vestibular disease. Store at room temperature. May cause sedation. Safe for occasional use.

Oral tablets: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. Administer 1 hr before anticipated motion sickness. Tablets may be crushed. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one.

CNS sedation (antihistamine effect). Anticholinergic effects: dry mouth, urinary retention, GI hypomotility, blurred vision. GI: vomiting (uncommon). Paradoxical CNS stimulation (rare — especially cats). Avoid in glaucoma, urinary obstruction.

For animals Avoid in patients with glaucoma or urinary obstruction (anticholinergic effects). Sedation may be marked. Not approved for use in food-producing animals. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Antihistamine — may cause drowsiness if accidentally ingested. Keep out of reach of children.

Contact your veterinarian. Meclizine overdose causes sedation and anticholinergic signs. Contact your veterinarian, a veterinary emergency clinic, or the ASPCA Animal Poison Control Center (888-426-4435) immediately. Do not induce vomiting unless specifically directed by a veterinary professional.