Mg Biologics C. Perfringens A R. Equi Plasma 1100 Injectable
General Drug Information and Indications
Hyperimmune equine plasma (Clostridium perfringens/Rhodococcus equi) for passive immunization of neonatal foals at risk for septicemia and failure of passive transfer.
Equine hyperimmune plasma (C. perfringens A + R. equi). Mechanism: plasma from horses hyperimmunized against Clostridium perfringens Type A and Rhodococcus equi contains high-titer specific antibodies (IgG) → passive immunization of foals via IV transfusion → immediate protection while foal develops active immunity.
Key information
Hyperimmune equine plasma. Refrigerate; check expiry. Warm to room temperature before IV infusion. Use IV set with filter. Monitor for transfusion reactions.
How to Give this Medication
IV infusion: administer via jugular catheter slowly using blood administration set with filter. Have epinephrine available. Monitor throughout infusion. Store refrigerated (2–8°C); do not freeze.
If a dose is missed
This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.
Side Effects
Transfusion reactions: fever, urticaria, hemolysis. Volume overload (neonatal foals — give slowly). Rare: anaphylaxis. Disease transmission minimized with screened donors.
Precautions
For animals
Administer IV slowly — monitor for transfusion reactions. Volume limits for neonatal foals. Have epinephrine available.
For people handling this medication
Administered by veterinary professionals only. No specific human precautions for caregivers beyond normal hygiene.
Overdose
Contact your veterinarian. Plasma transfusion reactions are managed by veterinary staff.
Mg Biologics C. Perfringens A R. Equi Plasma 1100 Injectable dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| MG BIOLOGICS C. PERFRINGENS A R. EQUI PLASMA 1100 INJECTABLE | — | Injectable | 1 | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Failure of Passive Transfer in Foals; Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com); Product labeling (MG Biologics)