Moxifloxacin Sol Hcl

General Drug Information and Indications

Fluoroquinolone antibiotic ophthalmic solution for bacterial conjunctivitis and corneal infections. Fourth-generation fluoroquinolone ophthalmic antibiotic (moxifloxacin HCl 0.5%). Mechanism: inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV → prevents DNA replication (bactericidal). Enhanced gram-positive activity compared to earlier fluoroquinolones (ciprofloxacin). Available as preservative-free ophthalmic solution. Key information Fluoroquinolone — ophthalmic use. For ophthalmic use only. Do not use in animals with corneal epithelial damage (delays healing). Avoid in growing animals systemically. Store at room temperature.

How to Give this Medication

Ophthalmic solution: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. Instill 1 drop into affected eye(s) q6–8h. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Side Effects

Ophthalmic: transient stinging/burning upon instillation. Conjunctival hyperemia. Systemic absorption minimal — systemic effects rare with topical ophthalmic use.

Precautions

For animals Topical ophthalmic — not for injection. Monitor response; if no improvement in 7 days, re-evaluate. For people handling this medication Wash hands thoroughly with soap and water after handling. Ophthalmic fluoroquinolone — avoid human eye contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Wash hands thoroughly with soap and water after handling. Keep out of reach of children.

Overdose

Ophthalmic product — contact your veterinarian if the animal shows any unusual signs after application.

Moxifloxacin Sol Hcl dosage forms

ProductStrengthFormSizeType
MOXIFLOXACIN SOL HCL 0.5%——1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)