Neo Poly Dex Opth Ointment
General Drug Information and Indications
Combination ophthalmic (neomycin/polymyxin B/dexamethasone) for bacterial and inflammatory ocular conditions.
Multi-component ophthalmic combination: neomycin (aminoglycoside antibacterial), polymyxin B (polypeptide antibacterial — membrane disruption), dexamethasone (potent corticosteroid — reduces inflammation and vascular permeability). Combined antibacterial/anti-inflammatory for mixed infectious-inflammatory ocular conditions.
Key information
Neomycin/polymyxin B/dexamethasone ophthalmic. CONTRAINDICATED in corneal ulcer — corticosteroid impairs healing. Do not use until ulcer ruled out. Neomycin allergy possible.
How to Give this Medication
Ophthalmic solution or ointment: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. Instill 1–2 drops or apply ribbon of ointment 3–4 times daily. Store at room temperature; protect from light.
If a dose is missed
Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.
Side Effects
Ophthalmic: transient stinging, burning. Neomycin: contact hypersensitivity, allergic conjunctivitis. Dexamethasone: risk of secondary fungal or viral infection (herpesvirus reactivation — do not use with herpetic ulcers). Increased IOP (steroid-induced glaucoma — monitor with prolonged use). Corneal epithelial healing delay (corticosteroid).
Precautions
For animals
Verify tympanic membrane integrity before otic use. Dexamethasone component: do not use in ulcerative keratitis or herpetic ocular disease (steroid reactivates herpesvirus). Prolonged ophthalmic use: risk of secondary fungal infection and steroid-induced IOP elevation (glaucoma).
For people handling this medication
Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Antibiotic/steroid ophthalmic — neomycin allergy risk. Dexamethasone: minimize skin contact. Avoid human eye contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention.
Overdose
Contact your veterinarian. Ophthalmic antibiotic combination — systemic toxicity from eye drops is unlikely.
Neo Poly Dex Opth Ointment dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| NEO POLY DEX OPH SUSP 5 MLS | — | Suspension | 1 | Commercial |
| NEO POLY DEX OPTH OINTMENT 3.5GM | 3.5 GM | Ointment | 1 | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)