Neo Poly Dex Opth Ointment

General Drug Information and Indications

Combination ophthalmic (neomycin/polymyxin B/dexamethasone) for bacterial and inflammatory ocular conditions. Multi-component ophthalmic combination: neomycin (aminoglycoside antibacterial), polymyxin B (polypeptide antibacterial — membrane disruption), dexamethasone (potent corticosteroid — reduces inflammation and vascular permeability). Combined antibacterial/anti-inflammatory for mixed infectious-inflammatory ocular conditions. Key information Neomycin/polymyxin B/dexamethasone ophthalmic. CONTRAINDICATED in corneal ulcer — corticosteroid impairs healing. Do not use until ulcer ruled out. Neomycin allergy possible.

How to Give this Medication

Ophthalmic solution or ointment: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. Instill 1–2 drops or apply ribbon of ointment 3–4 times daily. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Side Effects

Ophthalmic: transient stinging, burning. Neomycin: contact hypersensitivity, allergic conjunctivitis. Dexamethasone: risk of secondary fungal or viral infection (herpesvirus reactivation — do not use with herpetic ulcers). Increased IOP (steroid-induced glaucoma — monitor with prolonged use). Corneal epithelial healing delay (corticosteroid).

Precautions

For animals Verify tympanic membrane integrity before otic use. Dexamethasone component: do not use in ulcerative keratitis or herpetic ocular disease (steroid reactivates herpesvirus). Prolonged ophthalmic use: risk of secondary fungal infection and steroid-induced IOP elevation (glaucoma). For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Antibiotic/steroid ophthalmic — neomycin allergy risk. Dexamethasone: minimize skin contact. Avoid human eye contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention.

Overdose

Contact your veterinarian. Ophthalmic antibiotic combination — systemic toxicity from eye drops is unlikely.

Neo Poly Dex Opth Ointment dosage forms

ProductStrengthFormSizeType
NEO POLY DEX OPH SUSP 5 MLS—Suspension1Commercial
NEO POLY DEX OPTH OINTMENT 3.5GM3.5 GMOintment1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)