Neo/poly/gra Sol Op

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General Drug Information and Indications

Combination ophthalmic (neomycin/polymyxin B/gramicidin) for bacterial ocular surface infections. Ophthalmic antibacterial combination: neomycin (aminoglycoside), polymyxin B (polypeptide), gramicidin (channel-forming antibacterial disrupting gram-positive membranes). Preservative-free option for gram-positive and gram-negative surface infections. Key information Neomycin/polymyxin B/gramicidin ophthalmic — see neo poly gra entry. Do not use in corneal ulcer.

How to Give this Medication

Ophthalmic solution: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. Instill 1–2 drops into affected eye(s) q4–6h. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Side Effects

Transient stinging upon instillation. Neomycin: contact hypersensitivity/allergic conjunctivitis (most common adverse reaction). Minimal systemic absorption with topical ophthalmic use.

Precautions

For animals Neomycin: contact allergy sensitization possible. Verify tympanic membrane integrity before otic use. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Triple antibiotic ophthalmic — neomycin allergy risk. Avoid human eye contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention.

Overdose

Contact your veterinarian. Ophthalmic antibiotic — systemic toxicity from eye drops is very unlikely.

Neo/poly/gra Sol Op dosage forms

ProductStrengthFormSizeType
NEO POLY GRAM OPHTH SOLUTION—Solution—Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)