General Drug Information and Indications

Nepafenac (NSAID) ophthalmic suspension for post-operative ocular pain and inflammation in dogs. Non-steroidal ophthalmic prodrug (nepafenac 0.1% suspension). Mechanism: penetrates cornea → converted by intraocular hydrolases to active amfenac → inhibits COX-1 and COX-2 in uveal and retinal tissues → reduces prostaglandin-mediated post-operative pain, inflammation, and miosis inhibition. Key information Nepafenac ophthalmic NSAID — prodrug. For ophthalmic use only. Shake well. Store at room temperature. Do not use in animals with corneal ulcer.

How to Give this Medication

Ophthalmic suspension: Shake well before each use. well before use. Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. Instill 1 drop into affected eye(s) 3 times daily. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Side Effects

Ophthalmic: ocular discomfort, foreign body sensation, photophobia, increased lacrimation. Blurred vision. Corneal thinning with prolonged use (rare). Superficial punctate keratopathy.

Precautions

For animals Topical ophthalmic — not for injection. May slow corneal wound healing with prolonged use. Shake well before use. For people handling this medication Wash hands thoroughly with soap and water after handling. Ophthalmic NSAID — avoid human eye contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Wash hands thoroughly with soap and water after handling.

Overdose

Contact your veterinarian. Ophthalmic NSAID — systemic effects unlikely from eye drops.

Nevanac Sus dosage forms

ProductStrengthFormSizeType
NEVANAC SUS 0.1% OP——1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Nonsteroidal Anti-inflammatory Drugs in Animals (https://www.merckvetmanual.com/pharmacology/inflammation/nonsteroidal-anti-inflammatory-drugs-in-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)