Nexgard 10.1-24.0 Lbs Chewable Tab

Afoxolaner (isoxazoline) chewable ectoparasiticide for flea and tick infestations in dogs; monthly administration. Systemic isoxazoline ectoparasiticide (afoxolaner). Mechanism: potent antagonist of GABA-gated and glutamate-gated chloride channels in arthropod CNS → sustained neuronal excitation → paralysis and death of fleas and ticks within hours. Highly selective for insect/arachnid receptor subtypes over mammalian GABA-A receptors. Monthly oral chewable tablet. Key information Afoxolaner — isoxazoline. Store at room temperature. Dogs only. Not for cats. Use caution in dogs with neurological history (seizure risk reported). Monthly administration. Administer with food for best absorption.

Oral chewable tablet: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. or treat. Administer monthly. Use correct weight-band product. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember and resume monthly administration.

GI: vomiting, diarrhea, decreased appetite, hypersalivation, lethargy (most common). CNS: tremors, ataxia, seizures (rare — post-marketing; use caution in dogs with seizure history). Isoxazoline class adverse effects.

For animals Use with caution in dogs with known seizure history (isoxazoline class). Not for puppies <8 weeks or <4 lbs. Not approved for use in food-producing animals. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Isoxazoline chewable — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children.

Contact your veterinarian. NexGard overdose (afoxolaner) may cause vomiting, tremors, and ataxia. Contact your veterinarian, a veterinary emergency clinic, or the ASPCA Animal Poison Control Center (888-426-4435) immediately. Do not induce vomiting unless specifically directed by a veterinary professional.