Nitrofurazone/dexamethasone

Compounded topical antibacterial/anti-inflammatory preparation containing nitrofurazone (topical nitrofuran antibacterial) and dexamethasone (corticosteroid); used for treatment of infected, inflamed wounds and skin lesions in horses. Compounded topical combination: nitrofurazone (nitrofuran antibacterial — bactericidal via reactive radical intermediates) + dexamethasone (potent fluorinated corticosteroid — glucocorticoid receptor agonist reducing inflammation). Combined antibacterial/anti-inflammatory for infected inflamed wounds. Key information Topical antibacterial/corticosteroid. Do not use on large infected wounds without appropriate coverage. Corticosteroid absorption possible. Wear gloves.

Topical wound preparation: apply to clean wound using sterile technique; dress appropriately. Do not apply to large open wounds (systemic absorption). Change dressing as directed. External use only. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember. If the next dose is due within a few hours, skip the missed dose and resume the regular schedule. Never give a double dose.

Local: skin/wound irritation, drying effect. Dexamethasone: delayed wound healing, adrenal suppression with large-area/prolonged use. Nitrofurazone: contact sensitization with prolonged use.

For animals Topical and wound use only — not for systemic administration. Not approved for use in food-producing animals. (potential carcinogen — no withdrawal time established). Avoid on large open wounds (systemic absorption). For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Potential carcinogen — wear gloves when applying. Avoid prolonged skin contact. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention.

Contact your veterinarian. A single accidental extra dose of a corticosteroid is usually not a medical emergency, but signs to watch for include extreme lethargy, vomiting, increased thirst/urination, and muscle weakness. Contact your vet before giving the next dose.