Nitrofurazone In Propylene Glycol

Topical nitrofuran antibacterial for wound care, burns, and superficial infections in horses; compounded in various vehicles (DMSO, propylene glycol, ointments). Nitrofuran topical antibacterial (nitrofurazone 0.2% preparation). Mechanism: bacterial enzymatic reduction of nitro group → reactive intermediates that damage DNA, proteins, and ribosomes → bactericidal. Active against gram-positive and gram-negative bacteria. Topical and wound use only (systemic nitrofurans no longer used due to carcinogenicity concerns). Key information Topical antibacterial solution. For external wound use only. Wear gloves. Not for use in food-producing animals. May cause contact sensitization.

Topical wound preparation: apply to clean wound using sterile technique; dress appropriately. Do not apply to large open wounds (systemic absorption). Change dressing as directed. External use only. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one.

Topical: local irritation, erythema, pruritus. Contact dermatitis/hypersensitivity (sensitizer with prolonged use). Systemic absorption from large wounds: carcinogenic potential (nitrofurans — do not use in food animals). Not for systemic use.

For animals Topical and wound use only — not for systemic administration. Not approved for use in food-producing animals. (potential carcinogen — no withdrawal time established). Avoid on large open wounds (systemic absorption). For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Potential carcinogen — wear gloves when applying. Avoid prolonged skin contact. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention.

Contact your veterinarian immediately. Phenazopyridine is TOXIC TO CATS. In dogs, overdose causes methemoglobinemia and kidney damage. Contact your veterinarian, a veterinary emergency clinic, or the ASPCA Animal Poison Control Center (888-426-4435) immediately. Do not induce vomiting unless specifically directed by a veterinary professional.