Nystatin Topical Powder 1 Miu

Topical polyene antifungal for candidiasis and superficial fungal infections in horses, dogs, and cats. Polyene antifungal (nystatin). Mechanism: binds ergosterol in fungal cell membrane → forms membrane pores → leakage of potassium ions and cellular contents → fungicidal. Similar mechanism to amphotericin B but more toxic (topical use only). Not absorbed systemically. Active against Candida, Aspergillus. Powder, ointment, or combination otic products. Key information Antifungal topical powder. For external use only. Store at room temperature.

Topical (powder, cream, ointment): apply to affected area 2–4 times daily. Clean ear canal before instillation. Gently massage base of ear after application to distribute medication. Administer orally. May be given with food to improve compliance and reduce GI upset. (oral suspension — nystatin is not absorbed systemically; swish and swallow for oral candidiasis). Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Topical/otic: local irritation, erythema (uncommon). Contact sensitization (rare). GI (oral): nausea, vomiting, diarrhea (minimal — poorly absorbed). Systemic toxicity not expected with topical use.

For animals Topical/otic only — not systemically absorbed. Verify tympanic membrane integrity before otic use. Assess for concurrent bacterial infection (nystatin has no antibacterial activity). For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Avoid inhaling sprays or aerosols. Keep out of reach of children. Antifungal — generally safe to handle. Wash hands thoroughly with soap and water after handling.

Nystatin is not absorbed systemically from topical use. Contact your veterinarian if the animal ingests large amounts or shows unusual signs.