General Drug Information and Indications

Fluoroquinolone antibiotic ophthalmic solution for bacterial conjunctivitis, corneal ulcers, and ocular surface infections. Second-generation fluoroquinolone ophthalmic solution (ofloxacin 0.3%). Mechanism: inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV → prevents DNA replication (bactericidal). Broad-spectrum gram-positive and gram-negative coverage. Available as 0.3% ophthalmic solution. Key information Fluoroquinolone ophthalmic antibiotic. For ophthalmic use only. Do not use in growing animals systemically. Avoid in corneal ulcer situations where fluoroquinolone use is contraindicated. Store at room temperature.

How to Give this Medication

Ophthalmic solution: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. Instill 1–2 drops into affected eye(s) q2–4h initially. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Side Effects

Ophthalmic: transient stinging/burning. Mild conjunctival hyperemia. Systemic effects minimal with ophthalmic use. Crystalline precipitates (rare).

Precautions

For animals Topical ophthalmic only. Assess corneal integrity. Monitor response. For people handling this medication Wash hands thoroughly with soap and water after handling. Ophthalmic fluoroquinolone — avoid human eye contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Wash hands thoroughly with soap and water after handling.

Overdose

Ophthalmic product — systemic overdose unlikely. Contact your veterinarian if eye irritation persists or if the animal ingested the product.

Ofloxacin Dro dosage forms

ProductStrengthFormSizeType
OFLOXACIN DRO 0.3% OP———Commercial
OFLOXACIN DRO 0.3% OP———Commercial
OFLOXACIN DRO 0.3% OP———Commercial
OFLOXACIN DRO 0.3% OP———Commercial
OFLOXACIN DRO 0.3% OP———Commercial
OFLOXACIN DRO 0.3% OP———Commercial
OFLOXACIN DRO 0.3% OP (SOLA)———Commercial
OFLOXACIN OPTH SOLN 0.3% 10 MLS—Solution1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)