General Drug Information and Indications

Iohexol iodinated contrast agent for diagnostic imaging (myelography, urography, arthrography). Iohexol non-ionic iodinated contrast media. Mechanism: provides radiopaque (x-ray dense) iodine atoms in non-ionic water-soluble solution → allows radiographic visualization of body cavities, blood vessels, and CNS structures when injected. Low osmolality (287–884 mOsm/kg) → better tolerated than ionic contrast media. Renally excreted unchanged. Key information Iohexol — non-ionic iodinated contrast medium. Store at room temperature; protect from light. Warm to body temperature before injection. Risk of contrast reaction — have emergency drugs available. Single-use vial.

How to Give this Medication

IV or intrathecal contrast agent — administered by veterinary staff only. Ensure adequate hydration before and after. Use only appropriate concentrations for each route. Do not mix with other medications. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

Contrast reactions: nausea, vomiting, urticaria, pruritus, anaphylaxis (rare — pre-medicate if history of contrast reaction). Nephrotoxicity (contrast-induced nephropathy — hydrate before and after). Cardiovascular: hypotension, bradycardia (rarely with intravascular injection). CNS: neurotoxicity if used intrathecally (use appropriate low-concentration formulation).

Precautions

For animals Ensure adequate hydration before contrast administration — nephrotoxicity risk. Avoid in patients with severe renal impairment. Monitor for anaphylactic reactions. Not for intrathecal use except in appropriate low-concentration formulations. For people handling this medication Administered by veterinary professionals only. No specific human precautions for caregivers beyond normal hygiene.

Overdose

Contact your veterinarian. Iohexol contrast overdose causes kidney damage (contrast nephropathy) and cardiovascular effects. Managed by veterinary staff with IV fluid support.

Omnipaque dosage forms

ProductStrengthFormSizeType
OMNIPAQUE 30ML 300 MG/ML IV300 MG/ML——Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)